This has been done before, including a patent from about 30 years ago for UPS system purposes. I believe IBM also looked into this for data centers. One anecdote that I remember was that they found pluggable connections to be quite dangerous at these DC voltages, because of the chance for unplugging the DC while in operation. One study allowing using the ubiquitous IEC 60320 cables for the DC inlets (standard 3-prong PC power cables). That DC bus design was only at ~250VDC if I remember correctly (300V limit for IEC 60320?).
DC arcing does not quench like an AC arc does due to no inherent zero voltage crossing to naturally commutate the current to zero. So even DC fusing is a different animal - larger fuses are needed for the same power level. The telecom industry used to use -48VDC for central office powering and it was also found to be very dangerous. Telecom DC plant workers could be fired for using non-insulated tools due to the chance of causing fires and having bodily injury. Nothing like having all of your facial hair being singed off.
I see a learning curve coming again, and industries have to relearn past knowledge. It is kind of fascinating to see that happen over and over as power technology gets adopted in newer industries, such as wind power, solar, EV systems and chargers, and circling back again here in server farm applications.